Eric J. Simon

Biosketch / Results /

Eric J. Simon, Ph.D.

Professor Emeritus of Psychiatry and Biochemistry and Molecular Pharmacology; Research Professor;
Departments of Psychiatry and Biochemistry and Molecular Pharmacology

Contact Info

Address
1 Park Ave
Psychiatry Floor 8 Room 8-230B
1 Park Avenue
New York, NY 10016

646-754-4834
646-754-4781
Eric.Simon@nyumc.org

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Education

1951 — Dr. Simon received his Ph.D. degree in Organic Chemistry from the University of Chicago, Chicago, IL, Graduate Education
1951-1953 — Dr. Simon was a Postdoctoral Fellow in Biochemistry at Columbia University, College of Physicians & Surgeons, New York, NY, PostDoctoral Training

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Research Summary

Our research explores the neurochemistry of neuropeptides and their receptors with the main objective of understanding the structure and functions of the endogenous opioid system, i.e., opioid receptors and endogenous opioid peptides. We discovered opioid receptors in 1973 and continue to contribute actively to this area with an interdisciplinary investigative approach from molecular biology to behavioral pharmacology.

Part of our work is characterizing the major types of opioid receptors, mu, delta, and kappa. We showed that the binding proteins of these receptors can be separated by size; we also purified to homogeneity the mu binding site from bovine brain and have cloned this receptor. We reconstituted the mu binding protein, purifies from bovine brain in liposomes with G-protein, resulting in the restoration of selective, GTP-sensitive, high affinity mu agonist binding, and mu-specific stimulation of GTPase activity.

We also study receptor regulation by phosphorylation and sequestration, the nature of the sugar moieties of this glycoprotein and, by quantitative autoradiography, pathophysiological changes in opioid receptors. The cloning of the major opioid receptors makes available cDNA for studies, including determining regions involved in receptor activation and G-protein coupling, by site-directed mutagenesis and regulation of receptor gene expression, by in situ hybridization. Proteins that intertact with the carboxyl tail of the mu opioid receptor are under study. We also have an active program on opioid signaling via the MAP kinase pathway.

Research Interests

Neuropeptides and Their Receptors

Research Keywords

neuropeptides, opioids, receptors, signal transduction, site-directed mutagenesis

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

The interaction between the mu opioid receptor and filamin a
Simon, Eric J; Onoprishvili, Irma
2010 Dec;35(12):1859-1866, Neurochemical research
— id: 115420, year: 2010, vol: 35, page: 1859, stat: Journal Article,

The Neurobiology of Addiction: Where We Have Been and Where We Are Going
Koob GF; Simon EJ
2009 Jan;39(1):115-132, Journal of drug issues
— id: 138849, year: 2009, vol: 39, page: 115, stat: Journal Article,

Filamin A mutant lacking actin-binding domain restores mu opioid receptor regulation in melanoma cells
Onoprishvili, Irma; Ali, Solav; Andria, Matthew L; Shpigel, Adam; Simon, Eric J
2008 Oct;33(10):2054-2061, Neurochemical research
— id: 93299, year: 2008, vol: 33, page: 2054, stat: Journal Article,

Chronic morphine treatment up-regulates mu opioid receptor binding in cells lacking filamin A
Onoprishvili, Irma; Simon, Eric J
2007 Oct 26;1177:9-18, Brain research
— id: 75472, year: 2007, vol: 1177, page: 9, stat: Journal Article,

A member of the heat shock protein 40 family, hlj1, binds to the carboxyl tail of the human mu opioid receptor
Ancevska-Taneva, N; Onoprishvili, I; Andria, M L; Hiller, J M; Simon, E J
2006 Apr 7;1081(1):28-33, Brain research
— id: 63620, year: 2006, vol: 1081, page: 28, stat: Journal Article,

Opiates: neurobiology
Simon, Eric J
Substance abuse : a comprehensive textbook Philadelphia : Lippincott Williams & Wilkins, 2005,
— id: 5492, year: 2005, vol: , page: ?, stat: Chapter,

Interaction between the mu opioid receptor and filamin A is involved in receptor regulation and trafficking
Onoprishvili, Irma; Andria, Matthew L; Kramer, Hal K; Ancevska-Taneva, Natasa; Hiller, Jacob M; Simon, Eric J
2003 Nov;64(5):1092-1100, Molecular pharmacology
— id: 39018, year: 2003, vol: 64, page: 1092, stat: Journal Article,

Identification of a neurorestrictive suppressor element (NRSE) in the human mu-opioid receptor gene (vol 91, pg 73, 2001)
Andria, ML; Simon, EJ
2002 SEP 30 ;105(1-2):161-161, Brain research. Molecular brain research
— id: 33044, year: 2002, vol: 105, page: 161, stat: Journal Article,

Delta opioid activation of the mitogen-activated protein kinase cascade does not require transphosphorylation of receptor tyrosine kinases
Kramer, H Kenneth; Onoprishvili, Irma; Andria, Matthew L; Hanna, Kayane; Sheinkman, Karina; Haddad, Lisa B; Simon, Eric J
2002 ;2:5-5, BMC pharmacology
— id: 63621, year: 2002, vol: 2, page: 5, stat: Journal Article,

Identification of a neurorestrictive suppressor element (NRSE) in the human mu-opioid receptor gene
Andria ML; Simon EJ
2001 Jul 13;91(1-2):73-80, Brain research. Molecular brain research
— id: 21117, year: 2001, vol: 91, page: 73, stat: Journal Article,

Mu-, delta- and kappa-opioid receptor populations are differentially altered in distinct areas of postmortem brains of Alzheimer's disease patients
Mathieu-Kia AM; Fan LQ; Kreek MJ; Simon EJ; Hiller JM
2001 Mar 2;893(1-2):121-134, Brain research
— id: 63622, year: 2001, vol: 893, page: 121, stat: Journal Article,

Tyrosine phosphorylation of the delta-opioid receptor. Evidence for its role in mitogen-activated protein kinase activation and receptor internalization
Kramer HK; Andria ML; Esposito DH; Simon EJ
2000 Sep 15;60(6):781-792, Biochemical pharmacology
— id: 11563, year: 2000, vol: 60, page: 781, stat: Journal Article,

Mutation of tyrosine 318 (Y318F) in the delta-opioid receptor attenuates tyrosine phosphorylation, agonist-dependent receptor internalization, and mitogen-activated protein kinase activation [In Process Citation]
Kramer HK; Andria ML; Kushner SA; Esposito DH; Hiller JM; Simon EJ
2000 Jun 23;79(1-2):55-66, Brain research. Molecular brain research
— id: 11570, year: 2000, vol: 79, page: 55, stat: Journal Article,

mu and delta-opioid receptor agonists induce mitogen-activated protein kinase (MAPK) activation in the absence of receptor internalization
Kramer HK; Simon EJ
2000 Jul 24;39(10):1707-1719, Neuropharmacology
— id: 11613, year: 2000, vol: 39, page: 1707, stat: Journal Article,

Localization of promoter elements in the human mu-opioid receptor gene and regulation by DNA methylation
Andria ML; Simon EJ
1999 Jun 18;70(1):54-65, Brain research. Molecular brain research
— id: 56449, year: 1999, vol: 70, page: 54, stat: Journal Article,

Inactivation of the purified bovine mu opioid receptor by sulfhydryl reagents
Gioannini TL; Onoprishvili I; Hiller JM; Simon EJ
1999 Jan;24(1):37-42, Neurochemical research
— id: 63624, year: 1999, vol: 24, page: 37, stat: Journal Article,

Role of protein kinase C (PKC) in agonist-induced mu-opioid receptor down-regulation: I. PKC translocation to the membrane of SH-SY5Y neuroblastoma cells is induced by mu-opioid agonists
Kramer HK; Simon EJ
1999 Feb;72(2):585-593, Journal of neurochemistry
— id: 57326, year: 1999, vol: 72, page: 585, stat: Journal Article,

Role of protein kinase C (PKC) in agonist-induced mu-opioid receptor down-regulation: II. Activation and involvement of the alpha, epsilon, and zeta isoforms of PKC
Kramer HK; Simon EJ
1999 Feb;72(2):594-604, Journal of neurochemistry
— id: 48732, year: 1999, vol: 72, page: 594, stat: Journal Article,

The bovine mu-opioid receptor: cloning of cDNA and pharmacological characterization of the receptor expressed in mammalian cells
Onoprishvili I; Andria ML; Vilim FS; Hiller JM; Simon EJ
1999 Nov 10;73(1-2):129-137, Brain research. Molecular brain research
— id: 11915, year: 1999, vol: 73, page: 129, stat: Journal Article,

Cloning and characterization of a mu opioid receptor from bovine brain
Onoprishvili, I.; Andria, M. L.; Vilim, S. S.; Hiller, J. M.; Carr, K. D.; Simon, E. J.
1999 ;25(1-2):1476-1476, Abstracts (Society for Neuroscience)
— id: 92214, year: 1999, vol: 25, page: 1476, stat: Journal Article,

Functional significance of cysteine residues in the delta opioid receptor studied by site-directed mutagenesis
Ehrlich GK; Andria ML; Zheng X; Kieffer B; Gioannini TL; Hiller JM; Rosenkranz JE; Veksler BM; Zukin RS; Simon EJ
1998 Mar;76(3):269-277, Canadian journal of physiology & pharmacology
— id: 57141, year: 1998, vol: 76, page: 269, stat: Journal Article,

Activation of fos in mouse amygdala by local infusion of norepinephrine or atipamezole
Stone EA; Zhang Y; Hiller JM; Simon EJ; Hillman DE
1997 Dec 5;778(1):1-5, Brain research
— id: 7811, year: 1997, vol: 778, page: 1, stat: Journal Article,

Opioid receptor imaging and displacement studies with [6-O-[11C] methyl]buprenorphine in baboon brain
Galynker, I; Schlyer, D J; Dewey, S L; Fowler, J S; Logan, J; Gatley, S J; MacGregor, R R; Ferrieri, R A; Holland, M J; Brodie, J; Simon, E; Wolf, A P
1996 Apr;23(3):325-331, Nuclear medicine & biology
— id: 76239, year: 1996, vol: 23, page: 325, stat: Journal Article,

Autoradiographic comparison of [3H]DPDPE and [3H]DSLET binding: evidence for distinct delta 1 and delta 2 opioid receptor populations in rat brain
Hiller JM; Fan LQ; Simon EJ
1996 May 6;719(1-2):85-95, Brain research
— id: 57419, year: 1996, vol: 719, page: 85, stat: Journal Article,

Chronic food restriction alters mu and kappa opioid receptor binding in the parabrachial nucleus of the rat: a quantitative autoradiographic study
Wolinsky TD; Carr KD; Hiller JM; Simon EJ
1996 Jan 15;706(2):333-336, Brain research
— id: 8089, year: 1996, vol: 706, page: 333, stat: Journal Article,

Functional reconstitution of a highly purified mu-opioid receptor protein with purified G proteins in liposomes
Fan LQ; Gioannini TL; Wolinsky T; Hiller JM; Simon EJ
1995 Dec;65(6):2537-2542, Journal of neurochemistry
— id: 56812, year: 1995, vol: 65, page: 2537, stat: Journal Article,

Historical summary of NIDA supported opioid research: A tribute to NIDA on its 20th anniversary
Simon EJ
1995 ;152:42-44, NIDA research monograph series
— id: 8116, year: 1995, vol: 152, page: 42, stat: Journal Article,

Recent studies on a mu-opioid receptor purified from bovine striatum
Simon EJ
1995 May 10;757:324-331, Annals of the New York Academy of Sciences
— id: 56789, year: 1995, vol: 757, page: 324, stat: Journal Article,

Molecular characterization of human mu-opioid receptor gene: Demonstration of promoter activity
Andria ML; Ehrlich GK; Simon EJ
1994 ;54(1):9-10, Regulatory peptides
— id: 8099, year: 1994, vol: 54, page: 9, stat: Journal Article,

RECONSTITUTION IN LIPOSOMES OF A MU-OPIOID BINDING-PROTEIN PURIFIED TO HOMOGENEITY FROM BOVINE STRIATAL MEMBRANES
GIOANNINI, TL; FAN, LQ; HYDE, L; OFRI, D; HILLER, JM; SIMON, EJ
1994 FEB 21 ;78(2):S55-S56, Regulatory peptides
— id: 52527, year: 1994, vol: 78, page: S55, stat: Journal Article,

Immunohistochemical localization of mu-opioid receptors in rat brain using antibodies generated against a peptide sequence present in a purified mu-opioid binding protein
Hiller JM; Zhang Y; Bing G; Gioannini TL; Stone EA; Simon EJ
1994 Oct;62(3):829-841, Neuroscience
— id: 56651, year: 1994, vol: 62, page: 829, stat: Journal Article,

Antinociception following subarachnoid bestatin in rats
Wang BC; Li D; Hiller JM; Simon EJ; Turndorf H
1994 ;19:2S66-2S66, Regional anesthesia
— id: 47287, year: 1994, vol: 19, page: 2S66, stat: Journal Article,

Effects of chronic food restriction on mu and kappa opioid binding in rat forebrain: a quantitative autoradiographic study
Wolinsky TD; Carr KD; Hiller JM; Simon EJ
1994 Sep 12;656(2):274-280, Brain research
— id: 6781, year: 1994, vol: 656, page: 274, stat: Journal Article,

Effect of chronic food restriction on regional Kappa opioid receptor binding in the rat: A quantitative autoradiographic study
Wolinsky, T. D.; Carr, K. D.; Hiller, J. M.; Simon, E. J.
1994 ;20(1-2):752-752, Abstracts (Society for Neuroscience)
— id: 92221, year: 1994, vol: 20, page: 752, stat: Journal Article,

Opioids II
Adler, Martin W; Herz, Albert; Akil, H; Simon, Eric J
Berlin : Springer Verlag, 1993,
— id: 1766, year: 1993, vol: , page: , stat: ,

Opioids
Akil, H; Herz, Albert; Simon, Eric J
Berlin : Springer Verlag, 1993,
— id: 1760, year: 1993, vol: , page: , stat: ,

Reconstitution of a purified mu-opioid binding protein in liposomes: selective, high affinity, GTP gamma S-sensitive mu-opioid agonist binding is restored
Gioannini TL; Fan LQ; Hyde L; Ofri D; Yao YH; Hiller JM; Simon EJ
1993 Jul 30;194(2):901-908, Biochemical & biophysical research communications
— id: 42058, year: 1993, vol: 194, page: 901, stat: Journal Article,

Antisera against peptides derived from a purified mu-opioid binding protein recognize the protein as well as mu-opioid receptors in brain regions and a cell line
Gioannini TL; Yao YH; Hiller JM; Taylor LP; Simon EJ
1993 Oct;44(4):796-801, Molecular pharmacology
— id: 56531, year: 1993, vol: 44, page: 796, stat: Journal Article,

Alterations in delta opioid receptor levels in discrete areas of the neocortex and in the globus pallidus of the aging guinea pig: a quantitative autoradiographic study
Hiller JM; Fan LQ; Simon EJ
1993 Jun 18;614(1-2):86-98, Brain research
— id: 57304, year: 1993, vol: 614, page: 86, stat: Journal Article,

Immunohistochemical localization of mu opioid receptors in rat brain with antibodies against a peptide sequence derived from a purified opioid binding protein (OBP)
Hiller, J. M.; Bing, G.; Stone, E.; Gioannini, T. L.; Simon, E. J.
1993 ;19(1-3):74-74, Abstracts (Society for Neuroscience)
— id: 92502, year: 1993, vol: 19, page: 74, stat: Journal Article,

Evaluation of three portable suction devices
Simon EJ; Davidson JA; Boom SJ
1993 Sep;48(9):807-809, Anaesthesia
— id: 63628, year: 1993, vol: 48, page: 807, stat: Journal Article,

Photoaffinity ligands for the mu opioid receptor
Simon EJ; Fan LQ; Hiller JM; Seyed-Mozaffari A; Schultz AG; Archer S
1993 ;53(14):1173-1178, Life sciences
— id: 13314, year: 1993, vol: 53, page: 1173, stat: Journal Article,

The effect of chronic food restriction on mu opioid receptors in the rat: A quantitative autoradiographic study
Wolinsky, T. D.; Carr, K.; Hiller, J. M.; Simon, E. J.
1993 ;19(1-3):1154-1154, Abstracts (Society for Neuroscience)
— id: 92224, year: 1993, vol: 19, page: 1154, stat: Journal Article,

Immunoblots with rhodopsin antisera suggest that a purified mu opioid binding protein has structural characteristics of a G-protein-coupled receptor
Gioannini TL; Weiss ER; Johnson GL; Hiller JM; Simon EJ
1992 Jan 1;89(1):52-55, Proceedings of the National Academy of Sciences of the United States of America
— id: 13801, year: 1992, vol: 89, page: 52, stat: Journal Article,

Recent studies on a mu opioid binding protein purified from bovine striatal membranes
Gioannini TL; Yao YH; Hiller JM; Simon EJ
1992 ;119:34-38, NIDA research monograph series
— id: 13796, year: 1992, vol: 119, page: 34, stat: Journal Article,

Age-related changes in kappa opioid receptors in the guinea-pig brain: a quantitative autoradiographic study
Hiller JM; Fan LQ; Simon EJ
1992 Oct;50(3):663-673, Neuroscience
— id: 57443, year: 1992, vol: 50, page: 663, stat: Journal Article,

Chimeric enkephalin-cystatins: opioid binding and structure-activity relationships of inhibitory domains
Marks N; Berg MJ; Makofske RC; Swistok J; Simon EJ; Ofri D; Del Compare K; Danho W
1992 Jul-Aug;5(4):194-200, Peptide research
— id: 42059, year: 1992, vol: 5, page: 194, stat: Journal Article,

Lesioning of the nucleus basalis of Meynert has differential effects on mu, delta and kappa opioid receptor binding in rat brain: a quantitative autoradiographic study
Ofri D; Fan LQ; Simon EJ; Hiller JM
1992 May 29;581(2):252-260, Brain research
— id: 13592, year: 1992, vol: 581, page: 252, stat: Journal Article,

Characterization of solubilized opioid receptors: reconstitution and uncoupling of guanine nucleotide-sensitive agonist binding
Ofri D; Ritter AM; Liu YF; Gioannini TL; Hiller JM; Simon EJ
1992 Feb;58(2):628-635, Journal of neurochemistry
— id: 13710, year: 1992, vol: 58, page: 628, stat: Journal Article,

Sulfhydryl groups on opioid receptors revisited. Evidence for two sulfhydryl groups at or near the active site of the mu opioid receptor
Ofri D; Simon EJ
1992 Summer;2(2):109-119, Receptor
— id: 13795, year: 1992, vol: 2, page: 109, stat: Journal Article,

Opioid receptors and their biochemistry
Simon EJ; Gioannini TL; Yao YH; Hiller JM
1992 ;15 Suppl 1 Pt A:48A-49A, Clinical neuropharmacology
— id: 13797, year: 1992, vol: 15 Suppl 1 Pt A, page: 48A, stat: Journal Article,

Studies on mu-opioid-binding sites with peptide antibodies
Simon EJ; Gioannini TL; Yao YH; Hiller JM
1992 ;126:57-65, NIDA research monograph series
— id: 13793, year: 1992, vol: 126, page: 57, stat: Journal Article,

Effects of stress on opioid receptor binding in the rat central nervous system
Stein EA; Hiller JM; Simon EJ
1992 Dec;51(3):683-690, Neuroscience
— id: 62294, year: 1992, vol: 51, page: 683, stat: Journal Article,

Are the preservatives sodium bisulfite and ethylene diaminetetraacetate free from neurotoxic involvement?
Wang BC; Budzilovich G; Hiller JM; Simon EJ; Hillman DE; Li D; Turndorf H
1992 Oct;77(3):602-604, Anesthesiology
— id: 45792, year: 1992, vol: 77, page: 602, stat: Journal Article,

Distribution of 3H-morphine after lumbar epidural administration in unanesthetized rabbits
Wang BC; Hiller JM; Simon EJ; Hillman DE; Rosenberg C; Turndorf H
1992 Nov-Dec;17(6):334-339, Regional anesthesia
— id: 8205, year: 1992, vol: 17, page: 334, stat: Journal Article,

Analgesia following subarachnoid sodium ibuprofen in rats
Wang BC; Hiller JM; Simon EJ; Li D; Rosenberg C; Turndorf H
1992 ;77:A862-A862, Anesthesiology
— id: 47354, year: 1992, vol: 77, page: A862, stat: Journal Article,

Lumbar subarachnoid ethylenediaminetetraacetate induces hindlimb tetanic contractions in rats: prevention by CaCl2 pretreatment; observation of spinal nerve root degeneration
Wang BC; Li D; Hiller JM; Simon EJ; Budzilovich G; Hillman DE
1992 Dec;75(6):895-899, Anesthesia & analgesia
— id: 13356, year: 1992, vol: 75, page: 895, stat: Journal Article,

Examining the analgesic effect of epidural bestatin and its low dose combination with clonidine in rats
Wang BC; Li D; Hiller JM; Simon EJ; Rosenberg C; Turndorf H
1992 ;17:3S84-3S84, Regional anesthesia
— id: 47291, year: 1992, vol: 17, page: 3S84, stat: Journal Article,

Effects of parabrachial opioid antagonism on stimulation-induced feeding
Carr KD; Aleman DO; Bak TH; Simon EJ
1991 Apr 5;545(1-2):283-286, Brain research
— id: 14069, year: 1991, vol: 545, page: 283, stat: Journal Article,

Opioid receptors and endogenous opioid peptides
Simon EJ
1991 Jul;11(4):357-374, Medicinal research reviews
— id: 13988, year: 1991, vol: 11, page: 357, stat: Journal Article,

Subarachnoid disodium EDTA induces concentration-dependent tetanic contraction in rats: prevention by CaCl2 pretreatment
Wang BC; Li D; Hiller JM; Simon EJ; Budzilovich G
1991 ;75:A651-A651, Anesthesiology
— id: 47363, year: 1991, vol: 75, page: A651, stat: Journal Article,

Epidural EDTA induces tetanic contractions in rats
Wang BC; Li D; Hiller JM; Simon EJ; Budzilovich G; Turndorf H
1991 ;72:S312-S312, Anesthesia & analgesia
— id: 47232, year: 1991, vol: 72, page: S312, stat: Journal Article,

No-carrier-added (NCA) N-(3-[18F]fluoropropyl)-N-norbuprenorphine and N-(3-[18F]fluoropropyl)-N-nordiprenorphine--synthesis, anatomical distribution in mice and rats, and tomographic studies in a baboon
Bai LQ; Teng RR; Shiue CY; Wolf AP; Dewey SL; Holland MJ; Simon EJ
1990 ;17(2):217-227, International journal of radiation applications & instrumentation. Pt. B. Nuclear medicine & biology
— id: 63631, year: 1990, vol: 17, page: 217, stat: Journal Article,

Differential effects of cyanogen bromide on ligand binding by mu, delta and kappa opioid receptors
Hiller JM; Fan LQ; Simon EJ
1990 ;47(24):2225-2230, Life sciences
— id: 62235, year: 1990, vol: 47, page: 2225, stat: Journal Article,

Electrophilic alpha-methylene-gamma-lactone and isothiocyanate opioid ligands related to etorphine
Klein P; Nelson WL; Yao YH; Simon EJ
1990 Aug;33(8):2286-2296, Journal of medicinal chemistry
— id: 63629, year: 1990, vol: 33, page: 2286, stat: Journal Article,

Conjugate addition ligands of opioid antagonists. Methacrylate esters and ethers of 6 alpha- and 6 beta-naltrexol
Olsen LD; Klein P; Nelson WL; Yao YH; Simon EJ
1990 Feb;33(2):737-741, Journal of medicinal chemistry
— id: 63630, year: 1990, vol: 33, page: 737, stat: Journal Article,

Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex
Schoffelmeer AN; Yao YH; Gioannini TL; Hiller JM; Ofri D; Roques BP; Simon EJ
1990 Apr;253(1):419-426, Journal of pharmacology & experimental therapeutics
— id: 42061, year: 1990, vol: 253, page: 419, stat: Journal Article,

Cross-linking of 125I-beta-endorphin to rat striatal mu- and delta-opioid receptors under physiological conditions: evidence for an opioid receptor complex
Schoffelmeer AN; Yao YH; Simon EJ
1990 ;328:105-108, Progress in clinical & biological research
— id: 63633, year: 1990, vol: 328, page: 105, stat: Journal Article,

Brain stimulation-induced feeding alters regional opioid receptor binding in the rat: an in vivo autoradiographic study
Stein EA; Carr KD; Simon EJ
1990 Nov 19;533(2):213-222, Brain research
— id: 62163, year: 1990, vol: 533, page: 213, stat: Journal Article,

Stimulus induced feeding alters regional opiate receptor binding in the rat: an in vivo audioradiographic study
Stein EA; Carr KD; Simon EJ
1990 ;328:187-190, Progress in clinical & biological research
— id: 63632, year: 1990, vol: 328, page: 187, stat: Journal Article,

A preliminary evaluation of analgesic latency of epidural analgesics in rabbits
Wang BC; Hiller JM; Simon EJ; Dubzilovich G; Hillman DE; Turndorf H
1990 ;40:S127-S127, Pain
— id: 47260, year: 1990, vol: 40, page: S127, stat: Journal Article,

Epidural meperidine does not significantly increase urinary bladder size: a cystographic study in rabbits
Wang BC; Hiller JM; Simon EJ; Hillman DE; Li D; Rosenberg C; Turndorf H
1990 ;15:1S30-1S30, Regional anesthesia
— id: 47293, year: 1990, vol: 15, page: 1S30, stat: Journal Article,

Selection of vehicle for epidural meperidine influences nociceptive latency in rabbits
Wang BC; Hiller JM; Simon EJ; Hillman DE; Li D; Rosenberg C; Turndorf H
1990 Jun;37(4 Pt 2):S47-S47, Canadian journal of anaesthesia
— id: 45794, year: 1990, vol: 37, page: S47, stat: Journal Article,

Low dose epidural clonidine enhances morphine analgesia withou causing hypotension in rabbits
Wang BC; Hiller JM; Simon EJ; Li D; Rosenberg C; Turndorf H
1990 ;73:A806-A806, Anesthesiology
— id: 47374, year: 1990, vol: 73, page: A806, stat: Journal Article,

Subarachnoid EDTA induces hindlimb myoclonous in rats
Wang BC; Li D; Hiller JM; Simon EJ; Dubzilovich G; Hillman DE; Turndorf H
1990 ;73:A1259-A1259, Anesthesiology
— id: 47375, year: 1990, vol: 73, page: A1259, stat: Journal Article,

OPIOID LIGANDS RELATED TO TIFLUADOM
Archer, S; Seyedmozaffari, A; Simon, EJ; Gioannini, TL
1989 Nov-Dec;24(6):569-572, European journal of medicinal chemistry
— id: 31900, year: 1989, vol: 24, page: 569, stat: Journal Article,

Effects of the selective kappa opioid antagonist, nor-binaltorphimine, on electrically-elicited feeding in the rat
Carr KD; Bak TH; Simon EJ; Portoghese PS
1989 ;45(19):1787-1792, Life sciences
— id: 10828, year: 1989, vol: 45, page: 1787, stat: Journal Article,

Evidence for the presence of disulfide bridges in opioid receptors essential for ligand binding. Possible role in receptor activation
Gioannini TL; Liu YF; Park YH; Hiller JM; Simon EJ
1989 Jul;2(1):44-48, Journal of molecular recognition
— id: 10567, year: 1989, vol: 2, page: 44, stat: Journal Article,

Pharmacokinetics of [3H]-buprenorphine in the rat
Holland MJ; Carr KD; Simon EJ
1989 Apr;64(1):3-16, Research communications in chemical pathology & pharmacology
— id: 10690, year: 1989, vol: 64, page: 3, stat: Journal Article,

Cross-linking of human 125I-beta-endorphin to a mu-delta opioid receptor complex in rat striatum
Schoffelmeer AN; Yao YH; Simon EJ
1989 Jul 18;166(2):357-358, European journal of pharmacology
— id: 10545, year: 1989, vol: 166, page: 357, stat: Journal Article,

CNS REGIONAL CHANGES IN TRITIATED DIPRENORPHINE BINDING FOLLOWING ELECTRICALLY ELICITED FEEDING IN THE RAT
STEIN E A; CARR K D; SIMON E J
1989 ;15(1):896-896, Abstracts (Society for Neuroscience)
— id: 92230, year: 1989, vol: 15, page: 896, stat: Journal Article,

Distribution of 3H-morphine following lumbar subarachnoid injection in unanesthetized rabbits
Wang BC; Hiller JM; Simon EJ; Hillman DE; Rosenberg C; Turndorf H
1989 May;70(5):817-824, Anesthesiology
— id: 10634, year: 1989, vol: 70, page: 817, stat: Journal Article,

Is EDTA inocuous in the subarachnoid space?
Wang BC; Hiller JM; Simon EJ; Hillman DE; Spielholz N; Turndorf H
1989 ;14:2S72-2S72, Regional anesthesia
— id: 47294, year: 1989, vol: 14, page: 2S72, stat: Journal Article,

Is EDTA harmless in the subarachnoid space?
Wang BC; Hiller JM; Simon EJ; Hillman DE; Turndorf H
1989 ;71:A1142-A1142, Anesthesiology
— id: 47384, year: 1989, vol: 71, page: A1142, stat: Journal Article,

Recovery of lidocaine following interpleural injection in rabbit
Wang BC; Hiller JM; Simon EJ; Sue JL; Turndorf H
1989 ;71:A746-A746, Anesthesiology
— id: 47385, year: 1989, vol: 71, page: A746, stat: Journal Article,

OPPOSITE EFFECTS OF ROSTRAL AND CAUDAL VENTRICULAR INFUSION OF NOR-BINALTORPHIMINE ON STIMULATION-INDUCED FEEDING
BAK T; CARR K D; SIMON E J; PORTOGHESE P S
1988 ;14(2):1107-1107, Abstracts (Society for Neuroscience)
— id: 92231, year: 1988, vol: 14, page: 1107, stat: Journal Article,

ANTIBODIES TO DYNORPHIN A 1-8 AND 1-17 ELEVATE THRESHOLD FOR BRAIN STIMULATION-INDUCED FEEDING IN RAT
CARR K D; BAK T H; SIMON E J
1988 ;14(2):1107-1107, Abstracts (Society for Neuroscience)
— id: 92232, year: 1988, vol: 14, page: 1107, stat: Journal Article,

Regulation of electrically elicited feeding in the rat by CNS opioid peptides
Carr KD; Simon EJ
Regulatory roles of opioid peptides Weinheim : VCH Publishers, 1988,
— id: 3427, year: 1988, vol: , page: 378, stat: Chapter,

Affinity crosslinking of 125I-labeled human beta-endorphin to cell lines possessing either mu- or delta-type opioid binding sites
Keren O; Gioannini TL; Hiller JM; Simon EJ
1988 Feb 9;440(2):280-284, Brain research
— id: 11184, year: 1988, vol: 440, page: 280, stat: Journal Article,

CITATION CLASSIC - STEREOSPECIFIC BINDING OF THE POTENT NARCOTIC ANALGESIC [H-3]ETORPHINE TO RAT-BRAIN HOMOGENATE
Simon, EJ
1988 Oct 10;48(41):19-19, Current contents. Life sciences
— id: 31590, year: 1988, vol: 48, page: 19, stat: Journal Article,

Urinary retention after intrathecal morphine in rabbits
Wang BC; Hiller J; Simon E; Hillman D; Turndorf H
1988 ;13:1S34-1S34, Regional anesthesia
— id: 47298, year: 1988, vol: 13, page: 1S34, stat: Journal Article,

Intravenous cystogram for study of urinary retention following intrathecal morphine in unanesthetized rabbits
Wang BC; Hiller JM; Simon EJ; Hillman DE; Turndorf H
1988 Jul;68(6):962-964, Anesthesiology
— id: 45796, year: 1988, vol: 68, page: 962, stat: Journal Article,

Is rostral spread the sole cause of respiratory depression after intrathecal morphine?
Wang BC; Hiller Jm; Simon EJ; Hillman DE; Turndorf H
1988 ;13:2S30-2S30, Regional anesthesia
— id: 47299, year: 1988, vol: 13, page: 2S30, stat: Journal Article,

Effects of stress and beta-funal trexamine pretreatment on morphine analgesia and opioid binding in rats
Adams JU; Andrews JS; Hiller JM; Simon EJ; Holtzman SG
1987 Dec 28;41(26):2835-2844, Life sciences
— id: 23566, year: 1987, vol: 41, page: 2835, stat: Journal Article,

ANTIBODIES TO DYNORPHIN A 1-13 BUT NOT BETA ENDORPHIN INHIBIT ELECTRICALLY-ELICITED FEEDING IN THE RAT
CARR K D; BAK T H; GIOANNIN T L; SIMON E J
1987 ;13(2):877-877, Abstracts (Society for Neuroscience)
— id: 92233, year: 1987, vol: 13, page: 877, stat: Journal Article,

Antibodies to dynorphin A(1-13) but not beta-endorphin inhibit electrically elicited feeding in the rat
Carr KD; Bak TH; Gioannini TL; Simon EJ
1987 Oct 6;422(2):384-388, Brain research
— id: 11344, year: 1987, vol: 422, page: 384, stat: Journal Article,

IRREVERSIBLE LABELING OF OPIOID RECEPTORS WITH THE AID OF ARYLDIAZONIUM SALTS DERIVED FROM FENTANYL
GALZI, JL; ILIEN, B; SIMON, EJ; GOELDNER, M; HIRTH, C
1987 JAN 26 ;28(4):401-404, Tetrahedron letters
— id: 41743, year: 1987, vol: 28, page: 401, stat: Journal Article,

Selective changes in mu, delta and kappa opioid receptor binding in certain limbic regions of the brain in Alzheimer's disease patients
Hiller JM; Itzhak Y; Simon EJ
1987 Mar 17;406(1-2):17-23, Brain research
— id: 62164, year: 1987, vol: 406, page: 17, stat: Journal Article,

[3H]-BUPRENORPHINE DISSOCIATION FROM OPIATE RECEPTORS INVIVO
Holland, MJC; Carr, KD; Simon, EJ
1987 Mar 1;46(3):868-868, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 31267, year: 1987, vol: 46, page: 868, stat: Journal Article,

No-carrier-added (NCA) (+/-)-N-(3-[18F]fluoropropyl)-N-normetazocine-synthesis and PET studies in a baboon
Shiue CY; Teng RR; Bai LQ; Wolf AP; Arnett CD; Simon EJ
1987 ;14(2):119-122, International journal of radiation applications & instrumentation. Pt. B. Nuclear medicine & biology
— id: 63635, year: 1987, vol: 14, page: 119, stat: Journal Article,

Recent studies on heterogeneity and isolation of opioid receptors
Simon EJ
1987 ;76:35-41, NIDA research monograph series
— id: 11430, year: 1987, vol: 76, page: 35, stat: Journal Article,

Subunit structure and purification of opioid receptors
Simon EJ
1987 ;7(1-4):105-132, Journal of receptor research
— id: 62273, year: 1987, vol: 7, page: 105, stat: Journal Article,

Interaction with lectin of kappa opioid binding sites solubilized from human placenta
Valette A; Rouge P; Coulais E; Potonnier G; Cros J; Simon EJ
1987 Feb 9;40(6):535-540, Life sciences
— id: 63634, year: 1987, vol: 40, page: 535, stat: Journal Article,

Distribution of 3H morphine following lumbar epidural injection in rabbits
Wang BC; Hiller J; Hillman DE; Holland M; Simon E; Turndorf H
1987 ;12:30-31, Regional anesthesia
— id: 47300, year: 1987, vol: 12, page: 30, stat: Journal Article,

Distribution of 3H morphine following lumbar subarachnoid injection in rabbits
Wang BC; Hiller JM; Holland MJ; Simon EJ; Hillman DE; Turndorf H
1987 ;66:S185-S185, Anesthesia & analgesia
— id: 47250, year: 1987, vol: 66, page: S185, stat: Journal Article,

Distribution of 3H-morphine following lumbar epidural injection in rabbits
Wang BC; Hiller JM; Holland MJ; Simon EJ; Hillman DE; Turndorf H
1987 ;67:A253-A253, Anesthesiology
— id: 47410, year: 1987, vol: 67, page: A253, stat: Journal Article,

Sodium ions increase the binding of the antagonist peptide ICI 174864 to the delta-opiate receptor
Appelmans N; Carroll JA; Rance MJ; Simon EJ; Traynor JR
1986 Feb-Mar;7(2):139-143, Neuropeptides
— id: 63637, year: 1986, vol: 7, page: 139, stat: Journal Article,

OPPOSITE EFFECTS OF MEDIAL THALAMIC MU AND KAPPA OPIOID ACTIVITY ON MOTIVATIONAL-AFFECTIVE RESPONSES
CARR K D; SIMON E J
1986 ;12(2):939-939, Abstracts (Society for Neuroscience)
— id: 92235, year: 1986, vol: 12, page: 939, stat: Journal Article,

The direct demonstration of binding of mu, delta and kappa agonists to digitonin-solubilized opioid receptors from bovine striatum
Crema G; Gioannini TL; Hiller JM; Simon EJ
1986 ;75:9-12, NIDA research monograph series
— id: 63639, year: 1986, vol: 75, page: 9, stat: Journal Article,

Limbic regions of the brain of Alzheimer's disease patients show selective changes in mu, delta and kappa opioid receptor binding
Hiller JM; Itzhak Y; Simon EJ
1986 ;75:559-562, NIDA research monograph series
— id: 11441, year: 1986, vol: 75, page: 559, stat: Journal Article,

Identification of distinct binding site subunits of mu and delta opioid receptors
Howard AD; Sarne Y; Gioannini TL; Hiller JM; Simon EJ
1986 Jan 28;25(2):357-360, Biochemistry
— id: 62150, year: 1986, vol: 25, page: 357, stat: Journal Article,

SYNTHESIS AND EVALUATION OF FLUORINATED DERIVATIVES OF FENTANYL AS CANDIDATES FOR OPIATE RECEPTOR STUDIES USING POSITRON EMISSION TOMOGRAPHY
HWANG, DR; FELIU, AL; WOLF, AP; MACGREGOR, RR; FOWLER, JS; ARNETT, CD; HOLLAND, MJ; CARR, K; SIMON, EJ
1986 MAR ;23(3):277-293, Journal of labelled compounds & radiopharmaceuticals
— id: 41607, year: 1986, vol: 23, page: 277, stat: Journal Article,

Affinity crosslinking of 125I-human beta-endorphin to cell lines possessing either mu or delta type opioid binding sites
Keren O; Gioannini TL; Hiller JM; Simon EJ
1986 ;75:89-92, NIDA research monograph series
— id: 63640, year: 1986, vol: 75, page: 89, stat: Journal Article,

COMPUTER AUTOMATED STRUCTURE EVALUATION OF OPIATE ALKALOIDS
KLOPMAN, G; MACINA, OT; SIMON, EJ; MILLER, JM
1986 JAN ;27(3-4):299-308, Journal of molecular structure. Theochem
— id: 41615, year: 1986, vol: 27, page: 299, stat: Journal Article,

Progress in the characterization of the opioid receptor subtypes: peptides as probes. Future directions
Simon EJ
1986 ;70:155-174, NIDA research monograph series
— id: 63638, year: 1986, vol: 70, page: 155, stat: Journal Article,

Recent studies on opioid receptors: heterogeneity and purification
Simon EJ
1986 ;463:31-45, Annals of the New York Academy of Sciences
— id: 62263, year: 1986, vol: 463, page: 31, stat: Journal Article,

Antagonist-induced opiate receptor upregulation in cultures of fetal mouse spinal cord-ganglion explants
Tempel A; Crain SM; Peterson ER; Simon EJ; Zukin RS
1986 Mar;390(2):287-291, Brain research
— id: 63636, year: 1986, vol: 390, page: 287, stat: Journal Article,

Chloroacryloyl amides and alpha-methylenelactones from naltrexone, oxymorphone and fentanyl
Archer S; Michael J; Michael M; Simon EJ; Abdelhamid EM; Nelson WL; Koolpe GA
1985 Feb;5(4-6):395-398, Neuropeptides
— id: 63645, year: 1985, vol: 5, page: 395, stat: Journal Article,

Hybromet: a ligand for purifying opioid receptors
Archer S; Michael J; Osei-Gyimah P; Seyed-Mozaffari A; Zukin RS; Maneckjee R; Simon EJ; Gioannini TL
1985 Dec;28(12):1950-1953, Journal of medicinal chemistry
— id: 62219, year: 1985, vol: 28, page: 1950, stat: Journal Article,

Relative affinities of the quaternary narcotic antagonist, N-methyl levallorphan (SR 58002), for different types of opioid receptors
Bianchetti A; Dragonetti M; Giudice A; Tarantino A; Ferrarese N; Manara L; Appelmans N; Simon EJ
1985 Feb;5(4-6):379-382, Neuropeptides
— id: 62270, year: 1985, vol: 5, page: 379, stat: Journal Article,

Diphenhydramine potentiates narcotic but not endogenous opioid analgesia
Carr KD; Hiller JM; Simon EJ
1985 Feb;5(4-6):411-414, Neuropeptides
— id: 63644, year: 1985, vol: 5, page: 411, stat: Journal Article,

N-(3-Fluoropropyl)-N-normetazocine, a potentially useful opiate antagonist for opiate receptor studies with positron emission tomography (PET)
Feliu AL; Holland MJ; Carr KD; Fowler JS; Simon EJ
1985 Sep;49(3):323-336, Research communications in chemical pathology & pharmacology
— id: 62115, year: 1985, vol: 49, page: 323, stat: Journal Article,

Purification of an active opioid-binding protein from bovine striatum
Gioannini TL; Howard AD; Hiller JM; Simon EJ
1985 Dec 5;260(28):15117-15121, Journal of biological chemistry
— id: 63641, year: 1985, vol: 260, page: 15117, stat: Journal Article,

Covalent labeling of opioid receptors with radioiodinated human beta-endorphin. Identification of binding site subunit
Howard AD; de La Baume S; Gioannini TL; Hiller JM; Simon EJ
1985 Sep 5;260(19):10833-10839, Journal of biological chemistry
— id: 63642, year: 1985, vol: 260, page: 10833, stat: Journal Article,

COVALENT LABELING OF OPIOID RECEPTORS WITH RADIOIODINATED HUMAN BETA-ENDORPHIN - IDENTIFICATION OF BINDING-SITE SUBUNITS
Howard, AD; Delabaume, S; Hiller, JM; Simon, EJ
1985 ;44(3):481-481, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 30781, year: 1985, vol: 44, page: 481, stat: Journal Article,

An opiate receptor-associated aminopeptidase that degrades enkephalins
Hui KS; Gioannini T; Hui M; Simon EJ; Lajtha A
1985 Aug;10(8):1047-1058, Neurochemical research
— id: 60406, year: 1985, vol: 10, page: 1047, stat: Journal Article,

Characterization of specific binding sites for [3H](d)-N-allylnormetazocine in rat brain membranes
Itzhak Y; Hiller JM; Simon EJ
1985 Jan;27(1):46-52, Molecular pharmacology
— id: 63646, year: 1985, vol: 27, page: 46, stat: Journal Article,

Opioid agonists and antagonists. 6-Desoxy-6-substituted lactone, epoxide, and glycidate ester derivatives of naltrexone and oxymorphone
Koolpe GA; Nelson WL; Gioannini TL; Angel L; Appelmans N; Simon EJ
1985 Jul;28(7):949-957, Journal of medicinal chemistry
— id: 63643, year: 1985, vol: 28, page: 949, stat: Journal Article,

INTERACTIONS OF ACRYLOYL AMIDE DERIVATIVES OF NALTREXONE WITH OPIOID RECEPTORS
ABDELHAMID, EE; MICHAEL, MA; MICHAEL, J; ARCHER, S; SIMON, EJ
1984 ;43(3):584-584, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 41008, year: 1984, vol: 43, page: 584, stat: Journal Article,

Differential sensitivity of major types of opioid binding sites to U.V. irradiation
Aucelio JG; Hiller JM; Gioannini T; Simon EJ
1984 Dec;5(1-3):141-144, Neuropeptides
— id: 63649, year: 1984, vol: 5, page: 141, stat: Journal Article,

Analgesic effects of ethylketocyclazocine and morphine in rat and toad
Carr KD; Aleman DO; Holland MJ; Simon EJ
1984 Aug 27;35(9):997-1003, Life sciences
— id: 63650, year: 1984, vol: 35, page: 997, stat: Journal Article,

Potentiation of reward by hunger is opioid mediated
Carr KD; Simon EJ
1984 Apr 16;297(2):369-373, Brain research
— id: 63651, year: 1984, vol: 297, page: 369, stat: Journal Article,

Development of Met-enkephalin immunoreactivity in organotypic explants of fetal mouse spinal cord and attached dorsal root ganglia
Chalazonitis A; Groth J; Hiller JM; Simon EJ; Crain SM
1984 Feb;314(2):183-189, Brain research
— id: 63655, year: 1984, vol: 314, page: 183, stat: Journal Article,

Affinity chromatography of solubilized opioid binding sites using CH-Sepharose modified with a new naltrexone derivative
Gioannini TL; Howard A; Hiller JM; Simon EJ
1984 Mar 15;119(2):624-629, Biochemical & biophysical research communications
— id: 63652, year: 1984, vol: 119, page: 624, stat: Journal Article,

PARTIAL-PURIFICATION OF SOLUBILIZED OPIOID BINDING-SITES ON A NOVEL AFFINITY MATRIX
GIOANNINI, TL; HOWARD, A; HILLER, JM; SIMON, EJ
1984 ;43(3):542-542, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 41005, year: 1984, vol: 43, page: 542, stat: Journal Article,

Characterization of the selective inhibition of the delta subclass of opioid binding sites by alcohols
Hiller JM; Angel LM; Simon EJ
1984 Mar;25(2):249-255, Molecular pharmacology
— id: 63653, year: 1984, vol: 25, page: 249, stat: Journal Article,

Etorphine pharmacokinetics in the rat: experimental data and mathematical model
Holland MJ; Simon EJ
1984 Dec;5(1-3):65-68, Neuropeptides
— id: 63647, year: 1984, vol: 5, page: 65, stat: Journal Article,

MATHEMATICAL-MODEL FOR ETORPHINE PHARMACOKINETICS IN THE RAT
HOLLAND, MJC; SIMON, EJ
1984 ;43(3):750-750, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 41016, year: 1984, vol: 43, page: 750, stat: Journal Article,

Effect of digitonin on the binding of opiate agonists and antagonists to membrane-bound and soluble opioid binding sites
Itzhak Y; Hiller JM; Gioannini TL; Simon EJ
1984 Jan 23;291(2):309-315, Brain research
— id: 63656, year: 1984, vol: 291, page: 309, stat: Journal Article,

Solubilization and characterization of kappa opioid binding sites from guinea pig cerebellum
Itzhak Y; Hiller JM; Simon EJ
1984 Dec;5(1-3):201-204, Neuropeptides
— id: 63648, year: 1984, vol: 5, page: 201, stat: Journal Article,

Solubilization and characterization of mu, delta, and kappa opioid binding sites from guinea pig brain: physical separation of kappa receptors
Itzhak Y; Hiller JM; Simon EJ
1984 Jul;81(13):4217-4221, Proceedings of the National Academy of Sciences of the United States of America
— id: 63186, year: 1984, vol: 81, page: 4217, stat: Journal Article,

A novel phencyclidine analog interacts selectively with mu opioid receptors
Itzhak Y; Simon EJ
1984 Aug;230(2):383-386, Journal of pharmacology & experimental therapeutics
— id: 62229, year: 1984, vol: 230, page: 383, stat: Journal Article,

PCP-4-PH-4-OH SELECTIVELY INTERACTS WITH MU OPIOID RECEPTORS
ITZHAK, Y; SIMON, EJ
1984 ;43(4):953-953, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 40998, year: 1984, vol: 43, page: 953, stat: Journal Article,

Diastereomeric 6-desoxy-6-spiro-alpha-methylene-gamma-butyrolactone derivatives of naltrexone and oxymorphone. Selective irreversible inhibition of naltrexone binding in an opioid receptor preparation by a conformationally restricted michael acceptor ligand
Koolpe GA; Nelson WL; Gioannini TL; Angel L; Simon EJ
1984 Dec;27(12):1718-1723, Journal of medicinal chemistry
— id: 62221, year: 1984, vol: 27, page: 1718, stat: Journal Article,

Recent studies on opioid receptors: heterogeneity and isolation (the Nathan B. Eddy Memorial Award lecture)
Simon EJ
1984 Mar;49:5-13, NIDA research monograph series
— id: 63654, year: 1984, vol: 49, page: 5, stat: Journal Article,

SOLUBILIZATION OF KAPPA-OPIOID RECEPTORS FROM GUINEA-PIG CEREBELLUM
SIMON, EJ; ITZHAK, Y
1984 ;43(3):542-542, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 41003, year: 1984, vol: 43, page: 542, stat: Journal Article,

Quaternary derivatives of narcotic antagonists: stereochemical requirements at the chiral nitrogen for in vitro and in vivo activity
Bianchetti A; Nisato D; Sacilotto R; Dragonetti M; Picerno N; Tarantino A; Manara L; Angel LM; Simon EJ
1983 ;33 Suppl 1:415-418, Life sciences
— id: 63660, year: 1983, vol: 33 Suppl 1, page: 415, stat: Journal Article,

Effects of naloxone and its quarternary analogue on stimulation-induced feeding
Carr KD; Simon EJ
1983 Jan;22(1):127-130, Neuropharmacology
— id: 63657, year: 1983, vol: 22, page: 127, stat: Journal Article,

The role of opioids in feeding and reward elicited by lateral hypothalamic electrical stimulation
Carr KD; Simon EJ
1983 ;33 Suppl 1:563-566, Life sciences
— id: 63658, year: 1983, vol: 33 Suppl 1, page: 563, stat: Journal Article,

Evidence from opiate binding studies that heroin acts through its metabolites
Inturrisi CE; Schultz M; Shin S; Umans JG; Angel L; Simon EJ
1983 ;33 Suppl 1:773-776, Life sciences
— id: 63659, year: 1983, vol: 33 Suppl 1, page: 773, stat: Journal Article,

Evidence for the solubilization of multiple opioid binding sites from mammalian brain
Itzhak Y; Hiller JM; Gioannini TL; Simon EJ
1983 ;33 Suppl 1:191-194, Life sciences
— id: 63661, year: 1983, vol: 33 Suppl 1, page: 191, stat: Journal Article,

Medial thalamic lesions reduce the aversion-gating action of lateral hypothalamic stimulation
Carr KD; Bonnet KA; Simon EJ
1982 Aug 26;246(2):342-346, Brain research
— id: 63666, year: 1982, vol: 246, page: 342, stat: Journal Article,

Mu and kappa opioid agonists elevate brain stimulation threshold for escape by inhibiting aversion
Carr KD; Bonnet KA; Simon EJ
1982 Aug 12;245(2):389-393, Brain research
— id: 63667, year: 1982, vol: 245, page: 389, stat: Journal Article,

Exposure to 4-aminopyridine prevents depressant effects of opiates on sensory-evoked dorsal-horn network responses in spinal cord cultures
Crain SM; Crain B; Peterson ER; Hiller JM; Simon EJ
1982 Jul 19;31(3):235-240, Life sciences
— id: 63668, year: 1982, vol: 31, page: 235, stat: Journal Article,

Lectin binding of solubilized opiate receptors: evidence for their glycoprotein nature
Gioannini T; Foucaud B; Hiller JM; Hatten ME; Simon EJ
1982 Apr 14;105(3):1128-1134, Biochemical & biophysical research communications
— id: 62148, year: 1982, vol: 105, page: 1128, stat: Journal Article,

Solubilization in good yield of active opiate binding sites from mammalian brain
Gioannini TL; Howells RD; Hiller JM; Simon EJ
1982 Sep 20-27;31(12-13):1315-1318, Life sciences
— id: 63663, year: 1982, vol: 31, page: 1315, stat: Journal Article,

THE OPIATE RECEPTOR IS A GLYCOPROTEIN - EVIDENCE FROM LECTIN AFFINITY-CHROMATOGRAPHY
Gioannini, T; Foucaud, B; Hiller, JM; Hatten, MB; Simon, EJ
1982 ;41(4):1031-1031, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 30459, year: 1982, vol: 41, page: 1031, stat: Journal Article,

Solubilization and characterization of active opiate binding sites from mammalian brain
Howells RD; Gioannini TL; Hiller JM; Simon EJ
1982 Sep;222(3):629-634, Journal of pharmacology & experimental therapeutics
— id: 63665, year: 1982, vol: 222, page: 629, stat: Journal Article,

SOLUBILIZATION OF ACTIVE OPIATE BINDING-SITES FROM MAMMALIAN BRAIN
Howells, RD; Gioannini, TL; Hiller, JM; Simon, EJ
1982 ;41(5):1635-1635, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 30454, year: 1982, vol: 41, page: 1635, stat: Journal Article,

Multiple opiate binding sites in human brain regions: evidence for kappa and sigma sites
Itzhak Y; Bonnet KA; Groth J; Hiller JM; Simon EJ
1982 Sep 20-27;31(12-13):1363-1366, Life sciences
— id: 63662, year: 1982, vol: 31, page: 1363, stat: Journal Article,

Potential affinity labels for the opiate receptor based on fentanyl and related compounds
Maryanoff BE; Simon EJ; Gioannini T; Gorissen H
1982 Aug;25(8):913-919, Journal of medicinal chemistry
— id: 62220, year: 1982, vol: 25, page: 913, stat: Journal Article,

Binding characteristics of mu and kappa agonists in rat brain subcellular fractions
Monferini E; Adler MW; Simon EJ
1982 Sep 20-27;31(12-13):1295-1298, Life sciences
— id: 63664, year: 1982, vol: 31, page: 1295, stat: Journal Article,

Inactivation and solubilization of opiate receptors by phospholipases A2
Ruegg UT; Cuenoud S; Fulpius BW; Simon EJ
1982 Mar 8;685(3):241-248, Biochimica & biophysica acta
— id: 62152, year: 1982, vol: 685, page: 241, stat: Journal Article,

Opiate receptors and opioid peptides: an overview
Simon EJ
1982 ;398:327-339, Annals of the New York Academy of Sciences
— id: 62262, year: 1982, vol: 398, page: 327, stat: Journal Article,

The nature of opiate receptors in toad brain
Simon EJ; Hiller JM; Groth J; Itzhak Y; Holland MJ; Beck SG
1982 Sep 20-27;31(12-13):1367-1370, Life sciences
— id: 62237, year: 1982, vol: 31, page: 1367, stat: Journal Article,

Recent work on opiate receptors: heterogeneity and solubilization
Simon EJ; Hiller JM; Ruegg UT; Gioannini T; Howells RD; Groth J; Angel L; Bonnet KA
1982 ;33:311-319, Advances in biochemical psychopharmacology
— id: 62260, year: 1982, vol: 33, page: 311, stat: Journal Article,

Opiate receptor heterogeneity in human brain regions
Bonnet KA; Groth J; Gioannini T; Cortes M; Simon EJ
1981 Sep 28;221(2):437-440, Brain research
— id: 62161, year: 1981, vol: 221, page: 437, stat: Journal Article,

Multiple opiate receptors: alcohol selectively inhibits binding to delta receptors
Hiller JM; Angel LM; Simon EJ
1981 Oct 23;214(4519):468-469, Science
— id: 62256, year: 1981, vol: 214, page: 468, stat: Journal Article,

Characterization of phospholipase A inhibition of stereospecific opiate binding and its reversal by bovine serum albumin
Lin HK; Holland MJ; Simon EJ
1981 Jan;216(1):149-155, Journal of pharmacology & experimental therapeutics
— id: 63669, year: 1981, vol: 216, page: 149, stat: Journal Article,

Presence of leucine-enkephalin in organotypic explants of fetal mouse spinal cord
Naftchi NE; Abrahams SJ; Crain SM; Peterson ER; Hiller JM; Simon EJ
1981 ;2 Suppl 1:57-60, Peptides
— id: 63670, year: 1981, vol: 2 Suppl 1, page: 57, stat: Journal Article,

Characterization and partial purification of solubilized active opiate receptors from toad brain
Ruegg UT; Cuenod S; Hiller JM; Gioannini T; Howells RD; Simon EJ
1981 Jul;78(7):4635-4638, Proceedings of the National Academy of Sciences of the United States of America
— id: 62247, year: 1981, vol: 78, page: 4635, stat: Journal Article,

Effect of the position of the phenolic group in morphinans on their affinity for opiate receptor binding
Simon LD; Simon FR; Mohasci E; Berger L; Simon EJ
1981 Jun 15;28(24):2769-2772, Life sciences
— id: 62236, year: 1981, vol: 28, page: 2769, stat: Journal Article,

OPIATE RECEPTORS - SOME RECENT DEVELOPMENTS
SIMON, EJ
1981 ;2(6):155-158, Trends in pharmacological science
— id: 40330, year: 1981, vol: 2, page: 155, stat: Journal Article,

Opiate receptors and endorphins: Possible relevance to narcotic addiction
Simon, EJ
1981 ;1(1):13-31, Advances in alcohol & substance abuse
— id: 579892, year: 1981, vol: 1, page: 13, stat: Journal Article,

Endorphins, opiate receptors and their evolving biology
Smith JR; Simon EJ
1981 ;11:87-126, Pathobiology annual
— id: 63671, year: 1981, vol: 11, page: 87, stat: Journal Article,

Advances in endogenous and exogenous opioids : proceedings of the International Narcotic Research Conference
Takagi, Hiroshi; Simon, Eric J
Tokyo : Kodansha, 1981,
— id: 1763, year: 1981, vol: , page: , stat: ,

Specific, high affinity [3H]ethylketocyclazocine binding in rat central nervous system: lack of evidence for kappa receptors
Hiller JM; Simon EJ
1980 Sep;214(3):516-519, Journal of pharmacology & experimental therapeutics
— id: 62227, year: 1980, vol: 214, page: 516, stat: Journal Article,

Opiate binding sites in the retina: properties and distribution
Howells RD; Groth J; Hiller JM; Simon EJ
1980 Oct;215(1):60-64, Journal of pharmacology & experimental therapeutics
— id: 63673, year: 1980, vol: 215, page: 60, stat: Journal Article,

Benzodiazepine binding in chicken retina and its interaction with gamma-aminobutyric acid
Howells RD; Simon EJ
1980 Oct 3;67(1):133-137, European journal of pharmacology
— id: 63672, year: 1980, vol: 67, page: 133, stat: Journal Article,

Radioautography of binding of tritiated diprenorphine to opiate receptors in the rat
Pearson J; Brandeis L; Simon E; Hiller J
1980 Mar 31;26(13):1047-1052, Life sciences
— id: 62232, year: 1980, vol: 26, page: 1047, stat: Journal Article,

Solubilization of an active opiate receptor from Bufo marinus
Ruegg UT; Hiller JM; Simon EJ
1980 Jun 27;64(4):367-368, European journal of pharmacology
— id: 62174, year: 1980, vol: 64, page: 367, stat: Journal Article,

STUDY OF AGENTS EFFECTIVE IN SOLUBILIZING OPIATE RECEPTORS
RUEGG, UT; SIMON, EJ; HILLER, JM; FULPIUS, BW
1980 ;36(6):731-731, Experientia
— id: 98658, year: 1980, vol: 36, page: 731, stat: Journal Article,

Opiate receptors and their implications for drug addiction
Simon EJ
1980 Mar;30:303-308, NIDA research monograph series
— id: 63674, year: 1980, vol: 30, page: 303, stat: Journal Article,

Recent studies on interaction between opioid peptides and their receptors
Simon EJ; Bonnet KA; Crain SM; Groth J; Hiller JM; Smith JR
1980 ;22:335-346, Advances in biochemical psychopharmacology
— id: 63675, year: 1980, vol: 22, page: 335, stat: Journal Article,

Selective protection of stereospecific enkephalin and opiate binding against inactivation by N-ethylmaleimide: evidence for two classes of opiate receptors
Smith JR; Simon EJ
1980 Jan;77(1):281-284, Proceedings of the National Academy of Sciences of the United States of America
— id: 62240, year: 1980, vol: 77, page: 281, stat: Journal Article,

Development of tolerance to opiates and opioid peptides in organotypic cultures of mouse spinal cord
Crain SM; Crain B; Finnigan T; Simon EJ
1979 Nov 19;25(21):1797-1802, Life sciences
— id: 63677, year: 1979, vol: 25, page: 1797, stat: Journal Article,

Selective depression by opiates and opioid peptides of sensory evoked dorsal horn network responses in organized fetal mouse spinal cord cultures
Crain SM; Crain B; Peterson ER; Simon EJ
1979 ;22:375-378, Proceedings of the Western Pharmacology Society
— id: 63679, year: 1979, vol: 22, page: 375, stat: Journal Article,

3H-ethylketocyclazocine binding: lack of evidence for a separate kappa receptor in rats CNS
Hiller JM; Simon EJ
1979 Dec 20;60(4):389-390, European journal of pharmacology
— id: 63168, year: 1979, vol: 60, page: 389, stat: Journal Article,

Benzodiazepine binding sites are present in retina
Howells RD; Hiller JM; Simon EJ
1979 Dec 10-17;25(24-25):2131-2136, Life sciences
— id: 63676, year: 1979, vol: 25, page: 2131, stat: Journal Article,

In vitro studies of opiate receptors
Simon EJ
1979 ;20:31-51, Advances in biochemical psychopharmacology
— id: 63680, year: 1979, vol: 20, page: 31, stat: Journal Article,

Studies on membrane-bound opiate receptors
Simon EJ
1979 ;27:51-62, Progress in clinical & biological research
— id: 63681, year: 1979, vol: 27, page: 51, stat: Journal Article,

Opioid activity of synthetic and naturally occurring enkephalin peptides
Simon EJ; Bonnet KA; Hiller JM; Rieman MW; Merrifield RB
1979 Nov 15;28(22):3333-3337, Biochemical pharmacology
— id: 63678, year: 1979, vol: 28, page: 3333, stat: Journal Article,

Selective depression by opioid peptides of sensory-evoked dorsal-horn network responses in organized spinal cord cultures
Crain SM; Crain B; Peterson ER; Simon EJ
1978 Nov 17;157(1):196-201, Brain research
— id: 63682, year: 1978, vol: 157, page: 196, stat: Journal Article,

SELECTIVE DEPRESSION BY ENDORPHINS OF SENSORY-EVOKED SYNAPTIC NETWORK DISCHARGES IN DORSAL HORN OF SPINAL-CORD CULTURES
CRAIN, SM; CRAIN, B; PETERSON, ER; SIMON, EJ
1978 ;37(3):237-237, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 98686, year: 1978, vol: 37, page: 237, stat: Journal Article,

Opiate receptors in cultures of fetal mouse dorsal root ganglia (DRG) and spinal cord: predominance in DRG neurites
Hiller JM; Simon EJ; Crain SM; Peterson ER
1978 Apr 28;145(2):396-400, Brain research
— id: 62160, year: 1978, vol: 145, page: 396, stat: Journal Article,

DISTRIBUTION OF OPIATE RECEPTORS IN ORGANIZED CULTURES OF FETAL MOUSE SPINAL-CORD AND DORSAL ROOT-GANGLI
Hiller, JM; Simon, EJ; Crain, SM; Peterson, ER
1978 ;37(3):238-238, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 29949, year: 1978, vol: 37, page: 238, stat: Journal Article,

Phospholipase A inhibition of opiate receptor binding can be reversed by albumin
Lin HK; Simon EJ
1978 Jan 26;271(5643):383-384, Nature
— id: 62251, year: 1978, vol: 271, page: 383, stat: Journal Article,

EFFECT OF PHOSPHOLIPASES A ON OPIATE RECEPTOR ACTIVITY
Lin, HK; Simon, EJ
1978 ;176(SEP):126-126, Abstracts of papers (American Chemical Society)
— id: 29886, year: 1978, vol: 176, page: 126, stat: Journal Article,

REVERSAL BY BOVINE SERUM-ALBUMIN OF PHOSPHOLIPASE-A INHIBITION OF OPIATE RECEPTOR-BINDING
Lin, HK; Simon, EJ
1978 ;37(3):238-238, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 29839, year: 1978, vol: 37, page: 238, stat: Journal Article,

Effect of morphine analogues on chemotaxis in Escherichia coli
Persky-Brosh S; Young JR; Holland MJ; Simon EJ
1978 Jul;107(1):53-58, Journal of general microbiology
— id: 63683, year: 1978, vol: 107, page: 53, stat: Journal Article,

[Opiate receptors and endorphins at the central nervous system level]
Simon EJ
1978 ;19(5):379-387, Annales de l'anesthesiologie francaise
— id: 62145, year: 1978, vol: 19, page: 379, stat: Journal Article,

In vitro studies on opiate receptors and their ligands
Simon EJ; Hiller JM
1978 Feb;37(2):141-146, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 62180, year: 1978, vol: 37, page: 141, stat: Journal Article,

The opiate receptors
Simon EJ; Hiller JM
1978 ;18:371-394, Annual review of pharmacology & toxicology
— id: 62295, year: 1978, vol: 18, page: 371, stat: Journal Article,

CITATION CLASSIC - PREPARATION OF S-SUCCINYL COENZYME-A
Simon, EJ
1978 ;85(19):11-11, Current contents
— id: 29691, year: 1978, vol: 85, page: 11, stat: Journal Article,

Selective opiate depression of sensory-evoked synaptic networks in dorsal horn regions of spinal cord cultures
Crain SM; Peterson ER; Crain B; Simon EJ
1977 Sep 9;133(1):162-166, Brain research
— id: 63686, year: 1977, vol: 133, page: 162, stat: Journal Article,

Opiate receptors in the central nervous system
Simon EJ
1977 ;4:33-69, Current developments in psychopharmacology
— id: 63687, year: 1977, vol: 4, page: 33, stat: Journal Article,

Receptor affinity and pharmacological potency of a series of narcotic analgesic, anti-diarrheal and neuroleptic drugs
Stahl KD; van Bever W; Janssen P; Simon EJ
1977 Dec 1;46(3):199-205, European journal of pharmacology
— id: 63171, year: 1977, vol: 46, page: 199, stat: Journal Article,

The purification of antimorphine antibodies by affinity chromatography
Walker MC; Simon EJ
1977 Nov;203(2):360-364, Journal of pharmacology & experimental therapeutics
— id: 63684, year: 1977, vol: 203, page: 360, stat: Journal Article,

Ontological development of opiate receptors in rodent brain
Clendeninn NJ; Petraitis M; Simon EJ
1976 Dec 10;118(1):157-160, Brain research
— id: 62159, year: 1976, vol: 118, page: 157, stat: Journal Article,

The opiate receptors
Simon, E J
1976 Feb;1(1):3-28, Neurochemical research
— id: 652532, year: 1976, vol: 1, page: 3, stat: Journal Article,

Inhibition by levorphanol and related drugs of amino acid transport by isolated membrane vesicles from Escherichia coli
Holland MJ; Simon EJ
1975 May;7(5):530-537, Antimicrobial agents & chemotherapy
— id: 63694, year: 1975, vol: 7, page: 530, stat: Journal Article,

Metabolism of polyamines in mouse neuroblastoma cells in culture: formation of GABA and putreanine
Kremzner LT; Hiller JM; Simon EJ
1975 Dec;25(6):889-894, Journal of neurochemistry
— id: 63690, year: 1975, vol: 25, page: 889, stat: Journal Article,

ANATOMIC LOCALIZATION OF NARCOTIC ANALGESIC BINDING IN BRAIN
Pearson, J; Hiller, J; Simon, E
1975 ;34(1):101-101, Journal of neuropathology & experimental neurology
— id: 28583, year: 1975, vol: 34, page: 101, stat: Journal Article,

Kinetics of opiate receptor inactivation by sulfhydryl reagents: evidence for conformational change in presence of sodium ions
Simon EJ; Groth J
1975 Jun;72(6):2404-2407, Proceedings of the National Academy of Sciences of the United States of America
— id: 62243, year: 1975, vol: 72, page: 2404, stat: Journal Article,

Solubilization of a stereospecific opiate-macromolecular complex from rat brain
Simon EJ; Hiller JM; Edelman I
1975 Oct 24;190(4212):389-390, Science
— id: 63691, year: 1975, vol: 190, page: 389, stat: Journal Article,

Opiate receptors and their interactions with agnoists and antagonists
Simon EJ; Hiller JM; Edelman I; Groth J; Stahl KD
1975 Jun 15;16(12):1795-1800, Life sciences
— id: 62233, year: 1975, vol: 16, page: 1795, stat: Journal Article,

Further properties of stereospecific opiate binding sites in rat brain: on the nature of the sodium effect
Simon EJ; Hiller JM; Groth J; Edelman I
1975 Mar;192(3):531-537, Journal of pharmacology & experimental therapeutics
— id: 63695, year: 1975, vol: 192, page: 531, stat: Journal Article,

EVIDENCE FOR A CONFORMATIONAL CHANGE IN OPIATE RECEPTORS IN PRESENCE OF SODIUM
Simon, EJ; Groth, J
1975 ;34(3):713-713, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28561, year: 1975, vol: 34, page: 713, stat: Journal Article,

STUDIES ON OPIATE RECEPTOR-SITES IN CENTRAL NERVOUS-SYSTEM
Simon, EJ; Hiller, JM
1975 ;51(10):1190-1190, Bulletin of the New York Academy of Medicine
— id: 28510, year: 1975, vol: 51, page: 1190, stat: Journal Article,

Effects of levorphanol on phospholipid metabolism in the giant axon of the squid
Dole WP; Simon EJ
1974 Jan;22(1):183-185, Journal of neurochemistry
— id: 63700, year: 1974, vol: 22, page: 183, stat: Journal Article,

Affinity chromatography of morphine and related drugs
Simon EJ
1974 ;34:619-623, Methods in enzymology
— id: 63699, year: 1974, vol: 34, page: 619, stat: Journal Article,

OPIATE RECEPTORS IN HUMAN AND ANIMAL BRAIN
Simon, EJ
1974 ;5(7874):44-44, Journal de pharmacologie
— id: 28362, year: 1974, vol: 5, page: 44, stat: Journal Article,

Comparative studies on synaptosomes: uptake of (N-Me-3H)choline by synaptosomes from squid optic lobes
Dowdall MJ; Simon EJ
1973 Oct;21(4):969-982, Journal of neurochemistry
— id: 63703, year: 1973, vol: 21, page: 969, stat: Journal Article,

Distribution of stereospecific binding of the potent narcotic analgesic etorphine in the human brain: predominance in the limbic system
Hiller JM; Pearson J; Simon EJ
1973 Nov;6(3):1052-1062, Research communications in chemical pathology & pharmacology
— id: 63701, year: 1973, vol: 6, page: 1052, stat: Journal Article,

Inhibition by levorphanol of the induction of acetylcholinesterase in a mouse neuroblastoma cell line
Hiller JM; Simon EJ
1973 Jun;20(6):1789-1792, Journal of neurochemistry
— id: 63707, year: 1973, vol: 20, page: 1789, stat: Journal Article,

INHIBITION BY LEVORPHANOL OF PROLINE TRANSPORT BY ISOLATED MEMBRANE VESICLES FROM ESCHERICHIA-COLI
HOLLAND, MJC; SIMON, EJ
1973 ;32(3):600-&, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 39881, year: 1973, vol: 32, page: 600, stat: Journal Article,

POLYAMINE METABOLISM IN MOUSE NEUROBLASTOMA CELL-CULTURES
KREMZNER, LT; HILLER, JM; SIMON, EJ
1973 ;32(3):525-&, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 39880, year: 1973, vol: 32, page: 525, stat: Journal Article,

Interaction of ribonucleic acid polymerase from Escherichia coli with deoxyribonucleic acid. Inhibition of ribonucleic acid synthesis by interaction of luteoskyrin with the transcription complex
Ruet A; Sentenac A; Simon EJ; Bouhet JC; Fromageot P
1973 Jun 5;12(12):2318-2324, Biochemistry
— id: 63706, year: 1973, vol: 12, page: 2318, stat: Journal Article,

In search of the opiate receptor
Simon EJ
1973 Sep;266(3):160-168, American journal of the medical sciences
— id: 62143, year: 1973, vol: 266, page: 160, stat: Journal Article,

Stereospecific binding of the potent narcotic analgesic (3H) Etorphine to rat-brain homogenate
Simon EJ; Hiller JM; Edelman I
1973 Jul;70(7):1947-1949, Proceedings of the National Academy of Sciences of the United States of America
— id: 63704, year: 1973, vol: 70, page: 1947, stat: Journal Article,

The effect of levorphanol tartrate on ribonucleic acid synthesis in normal and regenerating rat liver
Becker FF; Rossman T; Reiss B; Simon EJ
1972 Jan;3(1):105-116, Research communications in chemical pathology & pharmacology
— id: 63710, year: 1972, vol: 3, page: 105, stat: Journal Article,

Coupling of a new, active morphine derivative to sepharose for affinity chromatography
Simon EJ; Dole WP; Hiller JM
1972 Jul;69(7):1835-1837, Proceedings of the National Academy of Sciences of the United States of America
— id: 63709, year: 1972, vol: 69, page: 1835, stat: Journal Article,

Effects of levorphanol on phospholipid metabolism and composition in Escherichia coli
Wurster, N; Elsbach, P; Rand, J; Simon, E J
1971 Nov 5;248(2):282-292, Biochimica & biophysica acta
— id: 41969, year: 1971, vol: 248, page: 282, stat: Journal Article,

The effects of the morphine analogue levorphanol on leukocytes. Metabolic effects at rest and during phagocytosis
Wurster, N; Elsbach, P; Simon, E J; Pettis, P; Lebow, S
1971 May;50(5):1091-1099, Journal of clinical investigation
— id: 41972, year: 1971, vol: 50, page: 1091, stat: Journal Article,

The effect of the morphine analog levorphanol on phagocytosing leukocytes. A morphologic study
Zucker-Franklin, D; Elsbach, P; Simon, E J
1971 Nov;25(5):415-421, Laboratory investigation
— id: 41970, year: 1971, vol: 25, page: 415, stat: Journal Article,

Reversible inhibition of RNA phage replication and macromolecular synthesis by levorphanol
Simon EJ; Garwes DJ; Rand J
1970 Sep 10;40(5):1134-1141, Biochemical & biophysical research communications
— id: 63712, year: 1970, vol: 40, page: 1134, stat: Journal Article,

Effects of narcotics on the giant axon of the squid
Simon EJ; Rosenberg P
1970 Jul;17(7):881-887, Journal of neurochemistry
— id: 63713, year: 1970, vol: 17, page: 881, stat: Journal Article,

Effect of levorphanol on putrescine transport in Escherichia coli
Simon EJ; Schapira L; Wurster N
1970 Nov;6(6):577-587, Molecular pharmacology
— id: 63711, year: 1970, vol: 6, page: 577, stat: Journal Article,

Inhibition of the synthesis of 5-S ribosomal RNA in Escherichia coli by levallorphan
Roschenthaler R; Devynck MA; Fromageot P; Simon EJ
1969 Jun 17;182(2):481-490, Biochimica & biophysica acta
— id: 63714, year: 1969, vol: 182, page: 481, stat: Journal Article,

Initiation of chains by RNA polymerase and the effects of inhibitors studied by a direct filtration technique
Sentenac A; Simon EJ; Fromageot P
1968 Jul 23;161(2):299-308, Biochimica & biophysica acta
— id: 63715, year: 1968, vol: 161, page: 299, stat: Journal Article,

Polyamines and inhibition of RNA synthesis in E. coli by levorphanol
Simon EJ; Cohen SS; Raina A
1966 Aug 12;24(3):482-488, Biochemical & biophysical research communications
— id: 63716, year: 1966, vol: 24, page: 482, stat: Journal Article,

The selective inhibition of ribosomal RNA synthesis in E. coli by 2,4-Dinitrophenol
Simon EJ; Van Praag D; Aronson FL
1966 Jan;2(1):43-49, Molecular pharmacology
— id: 63718, year: 1966, vol: 2, page: 43, stat: Journal Article,

Studies on the intracellular distribution and tissue binding of dihydromorphine-7,8-H3 in the rat
Van Praag D; Simon EJ
1966 May;122(1):6-11, Proceedings of the Society for Experimental Biology & Medicine
— id: 63717, year: 1966, vol: 122, page: 6, stat: Journal Article,

INHIBITION OF BACTERIAL GROWTH BY DRUGS OF THE MORPHINE SERIES
SIMON EJ
1964 May 1;144:543-544, Science
— id: 63720, year: 1964, vol: 144, page: 543, stat: Journal Article,

INHIBITION OF RNA SYNTHESIS IN ESCHERICHIA COLI BY LEVORPHANOL
SIMON EJ; VANPRAAG D
1964 May;51:877-883, Proceedings of the National Academy of Sciences of the United States of America
— id: 63721, year: 1964, vol: 51, page: 877, stat: Journal Article,

SELECTIVE INHIBITION OF SYNTHESIS OF RIBOSOMAL RNA IN ESCHERICHIA COLI BY LEVORPHANOL
SIMON EJ; VANPRAAG D
1964 Jun;51:1151-1158, Proceedings of the National Academy of Sciences of the United States of America
— id: 63719, year: 1964, vol: 51, page: 1151, stat: Journal Article,

Inhibition of synthesis of RNA in E. coli by the narcotic drug laevorphanol
SIMON EJ
1963 May 25;198:794-795, Nature
— id: 63722, year: 1963, vol: 198, page: 794, stat: Journal Article,

Turnover of muscle and liver proteins in mice with hereditary muscular dystrophy
SIMON EJ; GROSS CS; LESSELL IM
1962 Jan;96:41-46, Archives of biochemistry & biophysics. ABB
— id: 63723, year: 1962, vol: 96, page: 41, stat: Journal Article,

An impaired concentrating mechanism for amino acids in mutants of Escherichia coli resistant to L-canavanine and D-serine
SCHWARTZ JH; MAAS WK; SIMON EJ
1959 Apr;32:582-583, Biochimica & biophysica acta
— id: 63725, year: 1959, vol: 32, page: 582, stat: Journal Article,

In vitro effect of tocopherol metabolites on respiratory decline in dietary necrotic liver degeneration
SCHWARZ K; MERTZ W; SIMON EJ
1959 Apr;32:484-491, Biochimica & biophysica acta
— id: 63724, year: 1959, vol: 32, page: 484, stat: Journal Article,

The metabolism of vitamin E. II. Purification and characterization of urinary metabolites of alpha-tocopherol
EISENGART A; MILHORAT AT; SIMON EJ; SUNDHEIM L
1956 Aug;221(2):807-817, Journal of biological chemistry
— id: 63726, year: 1956, vol: 221, page: 807, stat: Journal Article,

The metabolism of vitamin E. I. The absorption and excretion of d-alpha-tocopheryl-5-methyl-C14-succinate
GROSS CS; MILHORAT AT; SIMON EJ
1956 Aug;221(2):797-805, Journal of biological chemistry
— id: 63727, year: 1956, vol: 221, page: 797, stat: Journal Article,